You will need an adequate Exhaust System to exhaust all vaporized materials to the outside of your facility.  What you get will vary depending on your system and how you will be using your system. Talk to the manufacturers about what they recommend. Most manufacturers will recommend (for a 25 watt system, a blower that will move a minimum of 235 CFM (cubic feet per minute) at 6 inches of static pressure. Check with local heating and air conditioning and air purification companies for the best products and prices.

If you are going to be making rubber stamps, or LASER processing plastic and/or acrylics, consider a charcoal filtration, bubbler, or sprayer type of exhaust system. This will cut down on odor issues and help protect operators, other employees, visitors and neighbors form potentially harmful fumes.

Paints, glues, varnishes, and other finishes may also produce potentially harmful fumes if concentrated. Other materials definitely should be researched before laser processing.

Additionally, some materials put off by-products, which are potentially harmful to exposed persons. Some materials might also put off toxic by-products, which might corrode machine parts or electronic connections. If you are unsure as to the makeup of a particular material, ask the material manufacturer for a material safety data sheet (MSDS). You may also want to experiment first before exposing large amounts of an unknown material to the laser.

Additionally, you will want to make sure that your exhaust system includes ductwork that is built to support the type of blower and materials you will be using. Also, make sure all vents and ducts remain open and free of debris.

The best advice is to engrave in a well-ventilated room, and use an exhaust system that works for the kind of laser processing you will be doing.